Major General George Pickett in the Civil War

Major General George Pickett in the Civil War Major General George E. Pickett was a noted Confederate division commander during the Civil War. A West Point graduate, he took part in the Mexican-American War and distinguished himself at the Battle of Chapultepec. With the beginning of the Civil War, Pickett joined the Confederate Army and was later wounded at the Battle of Gainess Mill in June 1862. Returning to action that fall, he took command of a division in Lieutenant General James Longstreets corps. An effective and charismatic leader, his men earned fame during the final phases of the Battle of Gettysburg when they were part on an assault on the Union lines. Picketts career was effectively ended by his defeat at the Battle of Five Forks on April 1, 1865. Early Life George Edward Pickett was born January 16/25/28, 1825 (the precise date is disputed) at Richmond, VA. The eldest child of Robert and Mary Pickett, he was raised at the familys Turkey Island plantation in Henrico County. Educated locally, Pickett later traveled to Springfield, IL to study law. While there, he befriended Representative John T. Stuart and may have had some contact with a young Abraham Lincoln. In 1842, Stuart secured an appointment to West Point for Pickett and the young man left his legal studies to pursue a military career. Arriving at the academy, Picketts classmates included future comrades and adversaries such George B. McClellan, George Stoneman, Thomas J. Jackson, and Ambrose P. Hill. West Point Mexico Though well-liked by his classmates, Pickett proved a poor student and was better known for his antics. A renowned prankster, he was viewed as someone of ability but who only sought to study enough to graduate. As a result of this mentality, Pickett graduated last in his class of 59 in 1846. While being the class goat often led to short or inglorious career, Pickett quickly benefited from the outbreak of the Mexican-American War. Posted to the 8th US Infantry, he took part in Major General Winfield Scotts campaign against Mexico City. Landing with Scotts army, he first saw fighting at the Siege of Vera Cruz. As the army moved inland, he took part in the actions at Cerro Gordo and Churubusco. On September 13, 1847, Pickett came to prominence during the Battle of Chapultepec which saw American forces capture a key fortification and break through Mexico Citys defenses. Advancing, Pickett was the first American soldier to reach the top of Chapultepec Castles walls. Battle of Chapultepec. Photograph Source: Public Domain In the course of the action, he retrieved his units colors when his future commander, James Longstreet, was wounded in the thigh. For his service in Mexico, Pickett received a brevet promotion to captain. With the end of the war, he was assigned to the 9th US Infantry for service on the frontier. Promoted to first lieutenant in 1849, he married Sally Harrison Minge, the  great-great-grandniece of William Henry Harrison, in January 1851. Frontier Duty Their union proved short-lived as she died in childbirth while Pickett was posted at Fort Gates in Texas. Promoted to captain in March 1855, he spent a brief period at Fort Monroe, VA before being sent west for service in the Washington Territory. The following year, Pickett oversaw the construction of Fort Bellingham overlooking Bellingham Bay. While there, he married a local Haida woman, Morning Mist, who gave birth to a son, James Tilton Pickett, in 1857. As with his past marriage, his wife died a short time later. In 1859, he received orders to occupy San Juan Island with Company D, 9th US Infantry in response to a growing border dispute with the British known as the Pig War. This had commenced when an American farmer, Lyman Cutler, had shot a pig belonging to the Hudsons Bay Company which had broken into his garden. As the situation with the British escalated, Pickett was able to hold his position and deterred a British landing. After he was reinforced, Scott arrived to negotiate a settlement. Joining the Confederacy In the wake of Lincolns election in 1860 and the firing on Fort Sumter the following April, Virginia seceded from the Union. Learning of this, Pickett left the West Coast with the goal of serving his home state and resigned his US Army commission on June 25, 1861. Arriving after the First Battle of Bull Run, he accepted a commission as a major in the Confederate service. Given his West Point training and Mexican service, he was quickly promoted to colonel and assigned to the Rappahannock Line of the Department of Fredericksburg. Commanding from a black charger he dubbed Old Black, Pickett was also known for his immaculate appearance and his flashy, finely tailored uniforms. Fast Facts: Major General George Pickett Rank: Major GeneralService: US Army, Confederate ArmyBorn: January 16/25/28, 1825 in Richmond, VADied: July 30, 1875 in Norfolk, VAParents: Robert and Mary PickettSpouse: Sally Harrison Minge, Morning Mist, LaSalle Sallie Corbell  Conflicts: Mexican-American War, Civil WarKnown For: Peninsula Campaign, Battle of Chancellorsville, Battle of Gettysburg, Battle of the Wilderness, Spotsylvania Court House, Siege of Petersburg, Battle of Five Forks The Civil War Serving under Major General Theophilus H. Holmes, Pickett was able to use his superiors influence to receive a promotion to brigadier general on January 12, 1862. Assigned to lead a brigade in Longstreets command, he performed competently during the Peninsula Campaign and took part in the fighting at Williamsburg and Seven Pines. With the ascension of  General Robert E. Lee to command of the army, Pickett returned to battle during the opening engagements of the Seven Days Battles in late June. In the fighting at Gaines Mill on June 27, 1862, he was hit in the shoulder. This injury necessitated a three-month leave to recover and he missed the Second Manassas and Antietam campaigns. Rejoining the Army of Northern Virginia, he was given command of a division in Longstreets Corps that September and was promoted to major general the following month. General James Longstreet, CSA. Photograph Source: Public Domain In December, Picketts men saw little action during the victory at the Battle of Fredericksburg. In the spring of 1863, the division was detached for service in the Suffolk Campaign and missed the Battle of Chancellorsville. While in Suffolk, Pickett met and fell in love with LaSalle Sallie Corbell. The two would be wed on November 13 and later had two children. Picketts Charge During the Battle of Gettysburg, Pickett was initially tasked with guarding the armys lines of communication through Chambersburg, PA. As a result, it did not reach the battlefield until the evening of July 2. During the previous days fighting, Lee had unsuccessfully assaulted the Union flanks south of Gettysburg. For July 3, he planned an attack on the Union center. For this he requested that Longstreet assemble a force consisting of Picketts fresh troops, as well as battered divisions from Lieutenant General A.P. Hills corps. Moving forward after a protracted artillery bombardment, Pickett rallied his men with the cry of, Up, Men, and to your posts! Dont forget today that you are from Old Virginia! Pushing across a wide field, his men neared the Union lines before being bloodily repulsed. In the fighting, all three of Picketts brigade commanders were killed or wounded, with only Brigadier General Lewis Armisteads men actually piercing the Union line. With his division shattered, Pickett was inconsolable over the loss of his men. Falling back, Lee instructed Pickett to rally his division in case of a Union counterattack. To this order, Pickett is often quoted as replying General Lee, I have no division. The Battle of Gettysburg. Photograph Courtesy of the Library of Congress Though the failed attack is more accurately known as Longstreets Assault or the Pickett-Pettigrew-Trimble Assault, it quickly earned the name Picketts Charge in the Virginia newspapers as he was the only Virginian of high rank to take part. In the wake of Gettysburg, his career began a steady decline despite receiving no criticism from Lee regarding the attack. Following the Confederate withdrawal to Virginia, Pickett was re-assigned to lead the Department of Southern Virginia and North Carolina. Later Career In the spring, he was given command of a division in the Richmond defenses where he served under General P.G.T. Beauregard. After seeing action during the Bermuda Hundred Campaign, his men were assigned to support Lee during the Battle of Cold Harbor. Remaining with Lees army, Pickett took part in the Siege of Petersburg that summer, fall, and winter. In late March, Pickett was tasked with holding the critical crossroads of Five Forks. On April 1, his men were defeated at the Battle of Five Forks, while he was two miles away enjoying a shad bake. The loss at Five Forks effectively undermined the Confederate position at Petersburg, forcing Lee to retreat west. During the retreat to Appomattox, Lee may have issued orders relieving Pickett. Sources conflict on this point, but regardless Pickett remained with the army until its final surrender on April 9, 1865. Paroled with the rest of the army, he briefly fled to Canada only to return in 1866. Settling in Norfolk with his wife Sallie (married November 13, 1863), he worked as an insurance agent. As with many former US Army officers who had resigned and gone south, he had difficulty obtaining a pardon for his Confederate service during the war. This was finally issued on June 23, 1874. Pickett died on July 30, 1875, and was buried in Richmonds Hollywood Cemetery.

A Genetics Definition of Homologous Chromosomes

A Genetics Definition of Homologous Chromosomes Homologous chromosomes are chromosome pairs (one from each parent) that are similar in length, gene position, and centromere location. The position of the genes on each homologous chromosome is the same. However, the genes may contain different alleles. Chromosomes are important molecules, as they contain DNA and the genetic instructions for the direction of all cell activity. They also carry genes that determine individual traits. Homologous Chromosomes Example A human karyotype shows the complete set of human chromosomes. Human cells contain 23 pairs of chromosomes, for a total of 46. Each chromosome pair represents a set of homologous chromosomes. One chromosome in each pair is donated from the mother and the other from the father during sexual reproduction. In a karyotype, there are 22 pairs of autosomes (non-sex chromosomes) and one pair of sex chromosomes. In males, the X and Y sex chromosomes are homologs. In females, both X chromosomes are homologs. Mitosis The purpose of mitosis (nuclear division) and cell division is to replicate cells for repair and growth. Before mitosis begins, chromosomes must be replicated to ensure that each cell retains the correct number of chromosomes after cell division. Homologous chromosomes replicate forming sister chromatids (identical copies of a replicated chromosome that are attached). After replication, the single-stranded DNA becomes double-stranded and has the familiar X shape. As the cell progresses through the stages of mitosis, sister chromatids are eventually separated by spindle fibers and divided between two daughter cells. Each separated chromatid is considered a full single-stranded chromosome. Interphase: Homologous chromosomes replicate forming sister chromatidsProphase: Sister chromatids move toward the center of the cellMetaphase: Sister chromatids align along the metaphase plate at the cells centerAnaphase: Sister chromatids are separated and pulled toward opposite cell polesTelophase: Chromosomes are separated into distinct nuclei After the cytoplasm is divided during cytokinesis, two new daughter cells are formed with the same number of chromosomes in each cell. Mitosis preserves the homologous chromosome number. Meiosis Meiosis is the mechanism for gamete formation and involves a two-stage division process. Prior to meiosis, homologous chromosomes replicate forming sister chromatids. In prophase I, sister chromatids pair up forming what is called a tetrad. While in close proximity, homologous chromosomes sometimes exchange sections of DNA. This is known as genetic recombination. Homologous chromosomes separate during the first meiotic division and sister chromatids separate during the second division. At the end of meiosis, four daughter cells are produced. Each cell is haploid and contains half the number of chromosomes as the original cell. Each chromosome has the appropriate number of genes, however, the alleles for the genes are different. The swapping of genes during homologous chromosome recombination produces genetic variation in organisms that reproduce sexually. Upon fertilization, haploid gametes become a diploid organism. Nondisjunction and Mutations Occasionally, problems arise in cell division that cause cells to divide improperly. Failure of chromosomes to separate correctly in mitosis or meiosis is called nondisjunction. Should nondisjunction occur in the first meiotic division, homologous chromosomes remain paired. This results in two daughter cells with an extra set of chromosomes and two daughter cells with no chromosomes. Nondisjunction may also occur in meiosis II when sister chromatids fail to separate prior to cell division. Fertilization of these gametes produces individuals with either too many or not enough chromosomes. Nondisjunction is often fatal or may produce chromosomal anomalies resulting in birth defects. In trisomy nondisjunction, cells contain an extra chromosome. In humans, this means that there are 47 total chromosomes instead of 46. Trisomy is seen in Down syndrome where chromosome 21 has an additional or partial chromosome. Nondisjunction may also produce abnormalities in sex chromosomes. Monosomy is a type of nondisjunction in which only one chromosome is present. Females with Turner syndrome have only one X sex chromosome. Males with XYY syndrome have an extra Y sex chromosome. Nondisjunction in sex chromosomes typically has less severe consequences than nondisjunction in autosomal chromosomes (non-sex chromosomes). Chromosome mutations can impact both homologous chromosomes and non-homologous chromosomes. A translocation mutation is a type of mutation in which a piece of one chromosome breaks off and is joined to another chromosome. This type of mutation occurs more often between non-homologous chromosomes and can be reciprocal (gene exchange between two chromosomes) or non-reciprocal (only one chromosome receives a new gene segment).